The basics: hx-swap-oob
This is a new idea: let your response decide its own target(s)!
<div id="my-update-div" hx-swap-oob="true">Updated html</div>
<div id="my-update-div-2" hx-swap-oob="true">More updated html elsewhere on the page</div>
<div id="my-update-div" hx-swap-oob="true">Updated html</div>
<div id="my-update-div-2" hx-swap-oob="true">More updated html elsewhere on the page</div>